Sunday, December 23, 2018

Marijuana and Parkinson Disease

Marijuana is legal in Canada and some of you may be giving or getting some for the holidays. The following is from a story by Marie Ellis, published in Medical News Today in 2016.

Interestingly  Marijuana helps people who are suffering from Parkinsons Disease. In a review published in the journal Parkinson's Disease led by Prof. Zvi Loewy, from the Touro College of Pharmacy in New York, NY, his findings suggest symptoms of the condition could be improved with marijuana.  

Parkinson's disease is the second most common neurological illness in the United States, causing tremors, slowness of movement, postural instability, and impaired balance and coordination.  in the U.S., Parkinson's disease (PD) affects about 1 million people. It is progressive, which means it gets worse over time, and it occurs when a person's brain stops producing dopamine.

Dopamine is a neurotransmitter that plays a key role in our movements as well as in cognitive and psychological functions.

There is currently no cure for the disease; treatments carry with them several limitations and do not slow the progression of PD. Professor Loewy and his team conducted a thorough literature review on studies of marijuana. The most compelling finding was that chemical components of marijuana yield benefits in the wake of different PD symptoms.

For example, Prof. Loewy notes that marijuana has been found to relieve pain in other diseases, adding that it should be studied for pain relief in people with PD. Pain affects nearly 50 percent of people with the condition, the researchers note.

But why is marijuana specifically promising for PD? According to the team, the cannabinoid compounds in marijuana bind to dopamine receptors to reduce the effects of reduced dopamine in the brain.


Essentially, the compounds replace the normal compounds that are adversely affected by Parkinson's. The big finding from their review centers around the anti-inflammatory and antioxidant effects of marijuana, which may prevent neuron damage.

Inflammation can damage neurons that produce dopamine - the lack of which contributes to movement problems in Parkinson's. So preventing neuron damage could slow PD progression.

There is a need for safer drugs to treat PD, adding that cannabis may provide a viable alternative or addition to the current treatment of Parkinson's disease.

There are risks to take into account, recent research has uncovered some downsides to marijuana use, including memory loss, increased osteoporosis risk, and impaired blood vessel function.

Furthermore, a study published in 2016 suggested marijuana use may reduce dopamine in the brain.


Given all of this, they concluded that further studies are needed to provide more data on efficacy, safety, pharmacokinetics, and interactions of cannabinoids.

Saturday, December 22, 2018

Do yourself a favour, help others

Older people who help and support others are also doing themselves a favour. In 2009 an international research team found that grandparents who care for their grandchildren on average live longer than grandparents who do not. 

The researchers conducted survival analyses of over 500 people aged between 70 and 103 years, drawing on data from the Berlin Aging Study collected between 1990 and 2009.

Most previous studies on the topic did not include grandparents who were primary or custodial caregivers. Instead, they compared grandparents who provided occasional childcare with grandparents who did not, as well as with older adults who did not have children or grandchildren but who provided care for others in their social network.

The results of their analyses show that this kind of caregiving can have a positive effect on the mortality of the carers. Half of the grandparents who took care of their grandchildren were still alive about ten years after the first interview in 1990. The same applied to participants who did not have grandchildren, but who supported their children - for example, by helping with housework. In contrast, about half of those who did not help others died within five years.


The researchers were also able to show that this positive effect of caregiving on mortality was not limited to help and caregiving within the family. The data analysis showed that childless older adults who provided others with emotional support, for example, also benefited. Half of these helpers lived for another seven years, whereas non-helpers on average lived for only another four years.

Friday, December 21, 2018

Get a handle on your finances

Only four more sleeps to Christmas day, if you are like many of us, you have completed your shopping to find the perfect gift for your loved ones. Or you could be one of the many men, like me, scrambling to find that last minute gift. If you are finished and you were able to get all of the gifts, let's hope you are under budget. Last year on average Canadians spent over $700 each on the holiday. For a family of four that is over $2000. 

At this time of the year, your financial literacy is having the knowledge, skills and confidence to make responsible financial decisions and to not go overboard.  By reviewing your finances now, you will be better able to:

Understand how to make day-to-day choices about how to pay off the Christmas bills before they arrive so you can stay on top of financial obligations;
Plan ahead about how to use your hard-earned dollars for savings for next years spending or when and how long it will take to pay off the current years spending. 

Stats Canada puts out some interesting Christmas stats, here are a few

Gifts of all kinds

Exchanging gifts is a big part of Christmas, not to mention Hanukkah and Eid. Some families might see some of these items in their Christmas stockings or left under the tree!
  • $5.1 billion — The value of food and beverages purchased at large retailers in Canada in December 2016. This was up 16.92% from average monthly sales of $4.35 billion for this category in 2016 and up 16.8% from sales in November 2016.
  • $459.9 million — The value of televisions and audio and video equipment purchased at large retailers in Canada in December 2016. This was up 121.3% from average monthly sales of $207.8 million for this category in 2016 and up 31.0% from sales in November 2016.
  • $417.8 million — The value of toys, games and hobby supplies, including electronic games, purchased at large retailers in Canada in December 2016. This was up 203.7% from average monthly sales of $137.6 million for this category in 2016 and up 38.8% from sales in November 2016.
  • $274.9 million — The value of computer hardware and software purchased at large retailers in Canada in December 2016. This was up 65.4% from average monthly sales of $166.3 million for this category in 2016 and up 11.9% from sales in November 2016.
  • $263.4 million — The value of small electrical appliances purchased at large retailers in Canada in December 2016. This was up 91.5% from average monthly sales of $137.6 million for this category in 2016 and up 33.0% from sales in November 2016.
  • $238.5 million — The value of tableware, kitchenware, cookware and bakeware purchased at large retailers in Canada in December 2016. This was up 82.1% from average monthly sales of $131.0 million for this category in 2016 and up 46.6% from sales in November 2016.
Do you know what will be under your tree?

Thursday, December 20, 2018

Gratitude in advance

Five more sleeps until Christmas day and the gathering of the family and the sharing of gifts. 

Something to think about "feeling gratitude in advance, before you even receive, as if you already had, whether for direction or abundance or anything else, opens the floodgates of joy".